PRP — Platelet-Rich Plasma

PRP (Platelet-Rich Plasma) is derived from 10–20 ml of your own blood, which is centrifuged to isolate a concentration rich in platelets and growth factors, then applied topically or injected into the skin following microneedling, laser, or subcision. Its role is to support recovery; PRP cannot fill atrophic scars on its own as a standalone treatment. Because it is autologous, the risk of allergic reactions is minimal.

Medically reviewed by BS.Ths.CKI Kim Kha — BonBoz Clinic

What is PRP and How Does It Work?

Platelets contain growth factors essential for wound healing and tissue regeneration. When concentrated and applied to skin that has undergone controlled micro-injury (such as after microneedling, laser resurfacing, or subcision), PRP is intended to accelerate skin recovery and optimize collagen production. Individual responses vary and depend on platelet quality, the preparation method, and the delivery technique.

The Real Role of PRP in Acne Scar Treatment

PRP is an adjunctive therapy, not a primary treatment: controlled micro-injury (needling, laser, subcision) is what actually triggers tissue remodeling, while PRP supports the recovery phase. Clinical studies indicate that combining PRP with microneedling or laser yields better outcomes in certain patient groups compared to monotherapy, but PRP cannot replace these core procedures. Setting realistic expectations prevents unnecessary spending on standalone PRP treatments.

Other Applications of PRP Beyond Acne Scars

PRP is also used to accelerate post-laser recovery, improve skin elasticity and hydration via mesotherapy/micro-injections (often referred to as facial PRP/PRF), and support hair loss management when indicated. The level of clinical evidence varies for each indication; our doctors will clearly explain what PRP can achieve and where evidence remains inconclusive.

Safety

Because it is derived from your own blood, PRP does not cause allergic reactions to the substance itself; potential risks stem from the procedure (aseptic standards during blood draw, processing, and application) and injection technique. The treatment must be performed by a physician in a medical facility with strict sterilization protocols.

At BonBoz

Our dermatologists determine whether PRP is suitable based on your skin goals and individual profile. Blood is drawn and prepared using a sterile single-use kit, then immediately applied following microneedling, laser, or subcision, or administered via micro-injections as indicated. PRP is never sold as a standalone treatment.

How is it performed?

Draw 10–20 ml of venous blood into specialized tubes and centrifuge for 10–15 minutes to separate the platelet-rich plasma (PRP). Following microneedling/laser/subcision, the physician applies PRP onto the newly channeled skin or performs micro-injections into the dermis using a fine needle. The entire procedure takes 45–60 minutes.

Before the procedure

Have a light meal before your blood draw; stay well-hydrated; avoid alcohol and non-steroidal anti-inflammatory drugs (NSAIDs) for 2–3 days prior (as they can affect platelets) as instructed; disclose any blood disorders, active infections, or current use of anticoagulants.

After the procedure

Follow the post-care instructions of the accompanying procedure (microneedling/laser). For mesotherapy: minor red marks and mild swelling may occur for 1–2 days; avoid makeup for 24 hours; apply sun protection; avoid saunas and steam rooms for 3 days.

Possible risks — your doctor explains them before treatment

Mild bruising and swelling at the injection site for 1–3 days
Risk of infection if blood collection, separation, or injection procedures are not sterile
Variable and unpredictable responses across individuals
Added cost with marginal additional benefit in certain cases

Who should NOT have this?

Hematologic disorders, thrombocytopenia, coagulopathy
Active systemic or localized infections
Currently on anticoagulant therapy without prior medical consultation
Active malignant diseases under treatment
Pregnant or breastfeeding (insufficient safety data — defer treatment)
Expectations that PRP monotherapy alone can fully fill pitted/atrophic scars

BS.Ths.CKI Kim Kha

Aesthetic Dermatology

Graduated as a General Practitioner — Tay Nguyen University (2018)
Specialist Level I in Dermatology — Pham Ngoc Thach University of Medicine, degree awarded in 2025
Medical Practicing Certificate No. 009784/ĐL-CCHN — Issued by the Department of Health of Dak Lak Province on 15/10/2021
Over 8 years of experience in aesthetic dermatology practice (since 2018), including over 4 years of practice with an official Medical Practicing Certificate
Primary Specialization in Plastic and Reconstructive Surgery; Certificates in Dermatological Procedures & Minor Surgery, Microsurgery, and Lasers & Light Therapies in Dermatology
Certificates in Dermal Fillers, Botox, and Thread Lifts; Certificates in Emergency Resuscitation and Infection Control
Formerly practiced at the Aesthetic Dermatology Unit — Post and Telecommunications General Hospital (2019–2021) and Venus Sunrise Clinic (2022–2024) before joining BonBoz Clinic (2025)
Former lecturer in Aesthetic Dermatology Theory at Ana Aesthetic Training School (2018–2019)
Over 5,000 clinical dermatology cases treated

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Frequently asked questions

Can PRP fill pitted acne scars?

It does not fill scars on its own. PRP aids recovery after microneedling, laser, or subcision—these procedures are what actually stimulate skin regeneration.

Is PRP safe?

Because it is autologous, there is no risk of an allergic reaction to the PRP itself. Risks lie in sterile technique and administration, which requires the procedure to be performed at a medical facility by a physician.

How much blood is drawn?

Typically 10–20 ml, which is equivalent to a routine blood test.

Does it hurt?

The blood draw feels like a standard blood test. For micro-injections, topical anesthesia is applied, resulting in only a mild stinging sensation.

How many sessions are needed?

It follows the protocol of the primary procedure (typically 3–4 sessions spaced 4–6 weeks apart). For standalone facial PRP, a course of 3 sessions spaced 4 weeks apart is followed by maintenance treatments.

What is the difference between PRP and PRF?

PRF is prepared without anticoagulants, forming a fibrin matrix that releases growth factors more slowly. Both are supportive modalities; the physician selects the appropriate option based on your clinical goals.

Can PRP treat hair loss?

It is indicated as a supportive treatment for hair loss with moderate evidence. A consultation is required to diagnose the underlying cause of hair loss beforehand.

What medications should be taken or avoided before PRP?

Avoid nonsteroidal anti-inflammatory drugs (NSAIDs) for a few days prior as instructed, as they can affect platelet function. Do not discontinue prescribed medications on your own.

When will results be visible?

Accelerated recovery is noticeable within the first week. Improvements in skin texture and elasticity become evident after 4–8 weeks and over multiple sessions.

Who performs the procedure at BonBoz?

Dermatologists assess, prescribe, and perform the procedure. Blood collection and centrifugation are conducted under strict sterile protocols at the clinic.