Mesotherapy — Micro-injections

Mechanism of Action

Mesotherapy delivers active nutrients directly into the superficial dermis via targeted micro-injections—bypassing the stratum corneum, where topical creams have very limited absorption—while the micro-injuries simultaneously stimulate natural skin repair and collagen synthesis. The customized cocktail is selected by the physician based on targeted outcomes: non-crosslinked hyaluronic acid for hydration, vitamin C and tranexamic acid for brightening, peptides and growth factors for regeneration, and sebum-regulating actives for acne-prone skin.

What Mesotherapy Can and Cannot Do

What it can do: achieve more hydrated, radiant, and smoother skin after a few sessions; support mild tone evening; improve superficial post-acne skin texture; and maintain the results of other treatments. What it cannot do: restore lost volume (requires dermal fillers), lift sagging skin (requires HIFU, thread lifts), eliminate deep atrophic scars (requires lasers, RF microneedling, TCA), or treat clinical skin diseases (requires prescription medication). Mesotherapy serves as an ideal "foundational" and maintenance treatment.

Treatment Interval — No One-Size-Fits-All Schedule

According to Dr. Kim Kha, MD, MSc, mesotherapy does not have a fixed schedule for everyone: during the initial intensive recovery phase, sessions may be scheduled weekly, every 2 weeks, or every 4 weeks depending on the skin condition; once the skin stabilizes, intervals can be extended to every 1–3 months or longer for maintenance. The cadence is individualized based on skin status, goals, and treatment response, rather than sold as fixed-session packages.

Indications

Dull, dehydrated, and devitalized skin; enlarged pores with mild oiliness; adjunctive support after scar or pigmentation treatments once the skin has stabilized; mild early-stage aging; and routine skin maintenance. Patients seeking dramatic improvements in deep wrinkles or volume loss will require alternative modalities.

Potential Risks to Know

Redness, mild swelling, injection papules lasting 1–3 days, pinpoint bruising, itching or irritation to ingredients (rare), temporary acne purging in oily skin, infection due to non-sterile technique (rare), and herpes reactivation. Risks increase significantly with unverified formulations or arbitrary mixing—only products officially registered for intradermal injection should be used.

At BonBoz

A cosmetic dermatologist analyzes the skin, determines the treatment goals (hydration, brightening, texture, oil control), and selects an appropriate registered cocktail; topical numbing is applied, and sterile mesotherapy injection techniques are performed with region-specific depth adjustments. A standard course consists of 4–6 sessions followed by maintenance; directly performed by physicians and seamlessly integrated into a comprehensive treatment plan with other modalities when indicated.