Karisma Rh Collagen: Recombinant Human Collagen Injections, How They Differ from HA, and Where to Get Them in Ho Chi Minh City
Karisma Rh Collagen is an injectable skin booster containing recombinant human type I collagen, intended for people who want to improve skin quality rather than add volume. The manufacturer, Taumedika SRL (Italy), classifies the product as a Class III injectable medical device and describes it as stimulating fibroblasts to produce collagen. Your doctor will decide after an examination whether this treatment is suitable for you.
✚Compiled from BonBoz Clinic clinical documentation — currently in medical review
Where to get Karisma Rh Collagen in Ho Chi Minh City: BonBoz Clinic
At BonBoz Clinic in Ho Chi Minh City, the doctor examines you, plans the treatment and injects Karisma Rh Collagen in person, in a clinic licensed by the Ho Chi Minh City Department of Health. According to the doctor in charge, the product carries full labels and a scannable authenticity code; if it isn’t suitable for you, the doctor won’t go ahead.
Address
66–68 Vo Van Tan, Xuan Hoa Ward (former District 3), Ho Chi Minh City
BS CKI Bùi Kim Kha — Specialist Level I in Dermatology (Pham Ngoc Thach University of Medicine), medical practising certificate No. 009784/ĐL-CCHN issued by the Dak Lak Department of Health
Opening hours
Monday–Sunday, 8:00–20:00
Karisma + HIFU combo: price and conditions
Karisma + HIFU combo
4,999,000 VND
Indications, treatment plan, number of sessions and suitable limits are determined by the doctor after an in-person examination.
Who it is for
People considering the Karisma + HIFU combo (from the video or offer) who want a doctor to assess whether it suits them before deciding.
Conditions
Dr. Kim Kha (BS CKI) examines you, advises you and draws up your own treatment plan before any treatment.
Treatment goes ahead only if the doctor finds it suitable and you agree.
Included
The combo includes Karisma and HIFU.
The doctor's examination, advice and individual plan before treatment.
Not included / notes
Anything outside the combo (if the doctor recommends it) is quoted separately before treatment; a confirmed quote has no extra charges.
Not suitable when
If the doctor finds it unsuitable, the treatment is not performed.
The box names KARISMA Rh Collagen and the manufacturer Taumedika (Rome, Italy) — compare with the brand’s official website.
Seals and labels are intact and there is a scannable authenticity code (as described by the doctor in charge at BonBoz); lot number and expiry date are printed clearly.
The product is opened in front of you; if in doubt, contact the manufacturer at the email address published on its official site (info@karismaofficial.com).
Do not accept products bought online or brought in by the injector.
When your skin starts to lose elasticity and smoothness but you don't need extra volume, it's common to hesitate between hyaluronic acid (HA) filler, skin booster and Karisma. Some people have already tried skin booster and are still unsure about the next step, while others come across ads promising to "look younger after a single injection." Choosing the wrong product group can cost you money without delivering what you actually want, for example expecting Karisma to create volume like a filler when that is not what the product is for. This page helps you understand what Karisma is, how it differs from HA, who can consider it, and how to choose a provider before you see a doctor.
What Karisma is and is not
In aesthetic dermatology, "Karisma" is short for KARISMA Rh Collagen; the line used for the face is called KARISMA FACE Rh Collagen. The product is made by Taumedika SRL (Rome, Italy). The name overlaps with several unrelated brands, such as hotel chains, resorts and spas called Karisma. This page covers only the injectable product. Karisma is also not a device or an energy-based technology like HIFU: it is a substance that a doctor injects into the skin.
What the manufacturer states about Karisma
Classification: Class III injectable medical device, resorbable. The manufacturer calls the product a "bio-restitutive soft filler".
Composition: recombinant human type I collagen alpha-1 polypeptide chain, high molecular weight hyaluronic acid and carboxymethylcellulose.
Mechanism, as described by the manufacturer: stimulates human fibroblasts to produce type I collagen.
This is the manufacturer's description; this page has not cited any independent study on how effective Karisma is. The manufacturer does not publish a universal protocol, maintenance schedule or level of improvement that applies to everyone, so the specific recommendation must be decided by your doctor after an examination. At the consultation, you can ask your doctor about the documentation for the product being used.
Is There an Age Limit for Karisma? Dr. Kha Answers
How Karisma differs from HA filler and HA skin booster
Volumizing HA filler
HA skin booster
Karisma Rh Collagen
Main composition
Cross-linked hyaluronic acid gel
Thin hyaluronic acid with little cross-linking
Recombinant human type I collagen, high molecular weight HA, carboxymethylcellulose
Main goal
Restoring volume, contouring the chin, cheeks, lips and temples
Hydration, improving smoothness and fine lines
As described by the manufacturer: stimulates fibroblasts to produce type I collagen (this page has not cited any independent study)
Immediate volume
Yes
No
Not a goal of the product
In short: if you need added volume or contour, HA filler is the more suitable group, and Karisma does not replace a volumizing filler. If you need to improve skin quality, your doctor may consider HA skin booster or Karisma after an examination. A detailed comparison that includes CaHA is on the page How HA, CaHA and Karisma differ.
Who can consider Karisma
Karisma is aimed at people who want to improve skin quality without needing added volume. Dr. Bui Kim Kha (Specialist Level I in Dermatology), who examines patients and performs Karisma at BonBoz Clinic, shares that Karisma is not a product only for older people. People over 18 who can make decisions for themselves may consider it. Being 18 does not mean you should have it; the doctor first looks at your skin and asks about your goals. The doctor advises seeing it as a supplementary option, "a product that gives some support to the natural aging process." According to Dr. Bui Kim Kha, Karisma does not make skin look "youthful" after a single injection, and she does not recommend that everyone should have it.
For the dermal filler group in general, the FDA states that safety in people under 22 is not known; the doctor takes this into account during the examination. If what you want is more volume or a change in contour, Karisma is not the right choice.
Where to have Karisma in Ho Chi Minh City
Whichever provider you choose, you should be able to verify three things:
The facility has an operating license from the Department of Health.
The person who performs the injection is a doctor with a practicing certificate.
The product has a label, lot number, expiry date and a way to verify authenticity.
BonBoz Clinic is at 66–68 Vo Van Tan, Xuan Hoa Ward, HCMC (in the former District 3), and holds two licenses from the Department of Health of Ho Chi Minh City: 10036/HCM-GPHĐ (Aesthetic) and 11113/HCM-GPHĐ (Dermatology). Dr. Bui Kim Kha (Specialist Level I in Dermatology, practicing certificate 009784/ĐL-CCHN) examines you and designs an individual plan before the procedure. In the video posted on 23 October 2026, Dr. Kha shows the clinic's Karisma box with its full labeling and a code to scan to verify authenticity.
Before you decide, the consultation tells you whether your skin suits Karisma or whether another approach is better, along with a specific quote; you can see the box, label and verification code before the injection (if you don't know how to scan it, ask the doctor to guide you when the box is opened). If you have tried skin booster and are still undecided, bring the details of your previous injection so the doctor can assess it.
First step: leave your phone number in the form at the bottom of the page, and the clinic will call you back to schedule a consultation with Dr. Bui Kim Kha. The doctor gives the quote in person before the procedure. If you want to ask a quick question first, you can message on Zalo or call the hotline.
Video by Dr. Bui Kim Kha, BonBoz Clinic, posted 23 October 2026 (embedded above)
Video by Dr. Bui Kim Kha: "Combo Karisma và HIFU tại BonBoz Clinic"
When should you see a doctor?
The skin in the injected area looks pale, gray, or bluish-purple and feels cold to the touch
Unusual, severe, or worsening pain that does not ease
Changes in vision or signs of a stroke: go to the emergency room immediately
The injected area is red, swollen, inflamed, and painful for a prolonged period
How is it performed?
Patients can check the product label and authentication code. The doctor cleanses and disinfects the skin area, then performs the injections according to the agreed treatment plan. The technique, amount of product and injection sites are determined by the doctor, tailored to each patient.
Before the procedure
Have an in-person consultation with the doctor, and fully disclose your history of allergies, medical conditions, current medications and pregnancy status. The doctor will assess your skin and explain the options and costs before any procedure.
After the procedure
Mild swelling, redness, and bruising at the injection site may occur and are usually temporary. Attend your follow-up appointments as scheduled, and notify your doctor immediately if you notice any of the signs listed in the warning section.
Possible risks — your doctor explains them before treatment
Bruising, redness, swelling, pain or tightness at the injection site
Itching or rash
Accidental injection into a blood vessel: rare, but regarded by the FDA as the most serious risk of injectable filler products
Who should NOT have this?
Patients under 18 unless a parent or legal guardian is present who understands and agrees to the treatment plan (BonBoz policy)
Inflamed or infected skin in the injection area
Bleeding disorders
Severe allergy or a history of anaphylaxis
Pregnancy or breastfeeding: for dermal fillers in general, the FDA states that safety in these two groups is not known
Expecting volume or contour changes that only filler can provide
How BonBoz uses it
HA filler for volume
Restores volume and contours the chin, cheeks, lips, or temples.
BonBoz Clinic displays a price list at the clinic and also provides a personalized quote for each case, as costs depend on the type of product, the amount used, the injection area and the treatment protocol. Your doctor will give you a clear quote after the examination and before the procedure, and once you have been examined and given the quote, the clinic does not add any other charges. Promotions run every month, so please call the hotline to find out about the current offers.
The final price follows the doctor’s recommendation after an in-person exam. A confirmed quote has no hidden extras.
Inside the BonBoz clinic
BS CKI Bùi Kim Kha
Dermatology — treatment of skin conditions
Graduated as a General Practitioner — Tay Nguyen University (2018)
Specialist Level I in Dermatology — Pham Ngoc Thach University of Medicine, degree awarded in 2025
Medical Practicing Certificate No. 009784/ĐL-CCHN — Issued by the Department of Health of Dak Lak Province on 15/10/2021
Over 8 years of experience in dermatology practice (since 2018), including over 4 years of practice with an official Medical Practicing Certificate
Primary Specialization in Plastic and Reconstructive Surgery; Certificates in Dermatological Procedures & Minor Surgery, Microsurgery, and Lasers & Light Therapies in Dermatology
Certificates in Dermal Fillers, Botox, and Thread Lifts; Certificates in Emergency Resuscitation and Infection Control
Formerly practiced at the Aesthetic Dermatology Unit — Post and Telecommunications General Hospital (2019–2021) and Venus Sunrise Clinic (2022–2024) before joining BonBoz Clinic (2025)
Former lecturer in Aesthetic Dermatology Theory at Ana Aesthetic Training School (2018–2019)
More than 5,000 non-surgical dermatology treatment cases
Choose a date, time slot and doctor — the clinic calls back to confirm during opening hours (08:00–20:00). Free consultation, no commitment.
Frequently asked questions
Where can I get Karisma done at a reputable clinic in Ho Chi Minh City?
Choose a place where you can verify three things: an operating license from the Department of Health; a doctor with a practicing certificate who performs the injection personally; and a product with a label, lot number and authentication code confirming it is genuine. BonBoz Clinic at 66–68 Vo Van Tan, Xuan Hoa Ward, HCMC (former District 3) discloses all three: operating licenses 10036/HCM-GPHĐ and 11113/HCM-GPHĐ, Dr. Bui Kim Kha (practicing certificate 009784/ĐL-CCHN) conducts the consultation and performs the procedure, and the product carries a code you can scan to authenticate it.
What is Karisma, and how does it differ from HA?
Karisma Rh Collagen is a Class III injectable medical device from Taumedika (Italy), containing recombinant human type I collagen together with high molecular weight HA and carboxymethylcellulose; the manufacturer describes the product as stimulating fibroblasts to produce type I collagen. HA filler is a cross-linked hyaluronic acid gel used to restore volume and contour, and it can be dissolved with the enzyme hyaluronidase. Karisma does not replace volumizing filler.
How much does Karisma cost in Ho Chi Minh City?
The price of Karisma varies between clinics because it depends on the amount of product, the injection area, the protocol, and whether it is combined with other treatment courses. At BonBoz Clinic (66–68 Vo Van Tan, Xuan Hoa Ward, HCMC), the doctor gives a quote after the consultation; once a quote has been given in person, the clinic adds no further charges. The clinic runs monthly promotions; call the hotline to find out the current offers.
Is "Karisma" the name of a hotel or spa?
In searches, Karisma may be the name of an unrelated hotel chain, resort or spa. In aesthetic dermatology, Karisma is the injectable product KARISMA Rh Collagen from Taumedika (Italy), injected by a doctor at a licensed medical facility.
Will I look younger right away after one Karisma session?
No. Dr. Bui Kim Kha advises seeing Karisma as a complementary solution that supports the skin as it ages naturally. Mild swelling right after the injection is a temporary reaction, not a result.
Is there an age limit for Karisma?
According to Dr. Bui Kim Kha, Karisma is not only for older people; people over 18 who can make decisions for themselves may consider it after a doctor's examination. Being eligible by age does not mean it is right for you: the doctor decides after the examination. For the class of dermal fillers in general, the FDA states that safety in people under 22 years old is not known; the doctor takes this into account during the examination. Under BonBoz's policy, people under 18 must be accompanied by a parent or guardian who understands and agrees to the protocol.
How often can Karisma be repeated?
The manufacturer does not publish a single schedule for everyone. Karisma can be repeated, but the interval and number of sessions are decided by the doctor after reassessing the skin at the follow-up visit.
How can I tell if Karisma is genuine?
The box shows the name KARISMA Rh Collagen and the manufacturer Taumedika (Rome, Italy); the label is intact, with a lot number, expiry date and a code you can scan to authenticate it; and the product is opened in front of you. If in doubt, contact the manufacturer through its official website. Do not have a product bought online injected.
Can Karisma be combined with HIFU?
It can. BonBoz Clinic offers a combined Karisma and HIFU course; according to Dr. Bui Kim Kha, the combination must be appropriately indicated and follow the right protocol for each person, and the doctor decides after the consultation.
We use cookies to understand how you use our website and to improve your experience. You can decline and still use all features. Personal Data Protection Policy
