Aesthetic Medicine

Deep nasolabial folds, hollow cheeks

Deep smile lines and sunken cheeks are signs of midface volume loss: cheek fat pads atrophy and shift downward with age, causing hollow cheeks and casting shadows along the nasolabial folds, making the face look gaunt and tired. In younger individuals, this can be caused by a low cheekbone structure or rapid weight loss.

Medically reviewed by BS.Ths.CKI Kim Kha — BonBoz Clinic

Why Do Smile Lines Deepen and Cheeks Become Hollow?

The midface consists of superficial and deep fat compartments supported by the cheekbones. With age, mild bone resorption occurs in the zygoma, retaining ligaments loosen, and fat pads atrophy and descend—causing the midcheek to hollow while the displaced fat accumulates along the nasolabial folds, making them appear deeper and casting shadows. Rapid weight loss, smoking, and excessive sun exposure accelerate this process. Younger individuals with naturally low cheekbones or a lean facial structure may also have prominent smile lines even without significant aging.

Why Shouldn't Filler Be Injected Directly into the Smile Lines?

The fold deepens because the midface tissue above it has sagged, not because the fold itself is simply "lacking" volume. Directly injecting large amounts of filler into the nasolabial fold may fill the crease, but the cheeks remain hollow, leaving the lower face looking heavy and the smile unnatural or stiff. The anatomically sound approach is to restore volume to the cheekbones and midcheek to provide structural lift from above, allowing the folds to soften naturally; only a minimal amount is placed directly in the crease if still needed. Furthermore, the facial artery runs through the nasolabial region, making proper injection technique and the use of a blunt cannula essential for safety.

HA Filler vs. Autologous Fat Grafting?

Hyaluronic Acid (HA) Fillers: Provide immediate results, allow volume adjustments across sessions, naturally dissolve over 12–18 months, and can be reversed with hyaluronidase if necessary. Ideal for moderate volume loss and those trying treatment for the first time. Autologous Fat Grafting: Uses your own fat (harvested from the abdomen or thighs) to restore volume to the cheeks, making it suitable for significant volume loss and long-term results; however, a portion of the transferred fat will be reabsorbed within 3–6 months—requiring overcorrection or touch-ups—and involves a longer recovery period with swelling.

What Factors Determine the Outcome?

The degree of volume deficit, concurrent skin laxity (severe laxity cannot be corrected by fillers alone and may require thread lifting or surgery), underlying bone structure, age, and appropriate product dosage—overfilling leads to an unnatural, "puffy" appearance.

How Does BonBoz Approach Smile Lines and Sunken Cheeks?

Our aesthetic dermatologists evaluate the face both at rest and during dynamic facial expressions (smiling), assess areas of volume loss and skin laxity, and capture standardized clinical photographs. The preferred approach focuses on structural midface lifting using HA fillers administered via cannula, using conservative amounts and staged sessions if necessary; autologous fat grafting or a referral to a plastic surgeon is recommended in cases of severe volume loss or pronounced skin laxity. Injections are performed directly by our physicians, with longevity, vascular risks, and safety management protocols thoroughly discussed prior to the procedure.

Severity levels

1

Mild — folds visible only when smiling, cheeks remain full

Filler is usually not required; maintain good skincare, sun protection, and monitor changes. A small amount of volume restoration can be performed if desired.

2

Moderate — folds noticeable at rest, mid-cheek hollows

Restore volume to the cheekbones and mid-cheek with a moderate amount of HA, adding only a minimal amount directly into the folds.

3

Severe — deep cheek hollowing, skin laxity, folds cast prominent shadows

Autologous fat grafting or high-volume HA delivered across multiple sessions; combined with thread lifts or surgical consultation if there is significant skin laxity.

When should you see a doctor?

  • Rapid cheek hollowing after weight loss or illness — a medical evaluation is required prior to volumizing.
  • Previous nasolabial fold filler done elsewhere resulting in lower face heaviness, stiffness when smiling, or asymmetry.
  • Pain, skin discoloration, or prolonged swelling at a previous injection site — an immediate examination is required to rule out vascular complications.
  • Deep folds accompanied by significant skin laxity — filler alone is insufficient; a consultation for thread lifting or surgery is recommended.

How BonBoz treats it

Cheek HA Dermal Fillers

Restoring volume to the cheekbones and midface using a cannula to provide tissue support and soften nasolabial folds; naturally dissolves over 12–18 months, with a dissolving agent available.

Learn about this method →

Mini Facelift Thread Lift

When deep folds are primarily caused by sagging skin and descended soft tissue: lifting the cheek tissue with barbed threads, combined with a minimal amount of filler.

Learn about this method →

HIFU Skin Lifting

High-Intensity Focused Ultrasound tightens the SMAS layer and cheek skin for mild to moderate laxity, combined with volume restoration.

Learn about this method →

Cost guidance

Dermal fillers are priced by volume (ml) and product type, while autologous fat transfer and thread lifts are priced per procedure. The doctor will provide a quote based on the treatment plan after an in-person consultation; the cost estimation tool provides a reference range only.

The final price follows the doctor’s recommendation after an in-person exam. A confirmed quote has no hidden extras.

Chân dung BS.Ths.CKI Kim Kha

BS.Ths.CKI Kim Kha

Aesthetic Dermatology

  • Graduated as a General Practitioner — Tay Nguyen University (2018)
  • Specialist Level I in Dermatology — Pham Ngoc Thach University of Medicine, degree awarded in 2025
  • Medical Practicing Certificate No. 009784/ĐL-CCHN — Issued by the Department of Health of Dak Lak Province on 15/10/2021
  • Over 8 years of experience in aesthetic dermatology practice (since 2018), including over 4 years of practice with an official Medical Practicing Certificate
  • Primary Specialization in Plastic and Reconstructive Surgery; Certificates in Dermatological Procedures & Minor Surgery, Microsurgery, and Lasers & Light Therapies in Dermatology
  • Certificates in Dermal Fillers, Botox, and Thread Lifts; Certificates in Emergency Resuscitation and Infection Control
  • Formerly practiced at the Aesthetic Dermatology Unit — Post and Telecommunications General Hospital (2019–2021) and Venus Sunrise Clinic (2022–2024) before joining BonBoz Clinic (2025)
  • Former lecturer in Aesthetic Dermatology Theory at Ana Aesthetic Training School (2018–2019)
  • Over 5,000 clinical dermatology cases treated
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Frequently asked questions

How many ml of filler are needed for smile lines?

It depends on the degree of volume loss and the area requiring support, typically 1–2 ml for both mid-cheek areas in moderate cases, which can be divided into multiple sessions if necessary. The exact amount is determined by the doctor during your consultation.

How long does filler last?

HA fillers in the cheek area typically last 12–18 months; areas with high mobility tend to metabolize faster. Periodic minor touch-ups help maintain stable results.

Is smile line filler dangerous?

This area contains the facial artery; injecting into the wrong anatomical plane can cause vascular occlusion and skin necrosis. Doctors use a blunt-tip cannula, inject slowly with small aliquots, and always have hyaluronidase on hand for immediate management.

Will my face look 'overfilled' or puffy?

When injected into the correct anatomical area with an appropriate volume, your face will only look naturally fuller. A puffy, overfilled appearance occurs when too much filler is used or injections are repeated too frequently.

Does autologous fat get reabsorbed?

Approximately 30–50% of the grafted fat is reabsorbed within the first 3–6 months; the remaining portion remains stable long-term. Doctors factor in slight overcorrection or schedule a touch-up session later.

What if the filler dissolves unevenly?

You can add a touch-up to the side that dissolves faster or use hyaluronidase if there is an obvious asymmetry. This is a key advantage of HA over non-dissolvable fillers.

How long after injection to see the final results?

Results are visible immediately after injection, but mild swelling lasts 3–7 days; the final result stabilizes after 2–4 weeks as the HA integrates with the tissue and hydrates.

Can people with naturally gaunt faces get volume restoration?

Yes, using HA fillers or autologous fat grafting in the cheekbones and mid-face. Young individuals with good skin elasticity typically achieve natural results with moderate volumes.

Are fillers enough for deep smile lines with skin sagging?

Usually not. Sagging skin requires lifting with thread lifts, HIFU, or surgery; dermal fillers serve only as a supportive treatment.

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